Statin Myths and Facts

Posted 06/11/25
Statins are a helpful medication used to reduce the level of cholesterol in the blood. Statins have been shown to decrease the future risk of heart attacks, strokes, and death, even when cholesterol levels are normal.
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How Can a Statin Help Me?

One way to lower your risk of cardiovascular disease is by keeping your cholesterol in a healthy range. Making good lifestyle choices, such as eating nonprocessed foods low in saturated fats and exercising regularly are great ways to keep your cholesterol levels in a healthy range. There are times when lifestyle changes are not enough, and your health care provider may prescribe a statin to help.

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Who Should Take a Statin?

People with cardiovascular disease are at increased risk of problems like heart attack, stroke or even death. Statin medications can reduce the risk of a heart attack or stroke. American Heart Association guidelines recommend people in any of these groups should talk to their provider about the benefits and risks of statin therapy

  • Adults with a history of cardiovascular disease (CVD), including stroke, caused by atherosclerosis
  • Those with LDL-C level of greater than 190 mg/dL
  • Adults 40-75 years with diabetes, regardless of your cholesterol level 
  • Adults 40-75 years with LDL-C level of 70-189 mg/dL and a 5% to 19.9% 10-year risk of developing CVD from atherosclerosis and risk-enhancing factors (ask your provider about your 10-year risk)
  • Adults 40-75 years with LDL-C level of 70-189 mg/dL and a 20% or greater 10-year risk of developing CVD from atherosclerosis (ask your provider about your 10-year risk)
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Examples of Statins and Side Effects

Some common statins are atorvastatin, rosuvastatin, simvastatin, pravastatin and lovastatin. Statins have few side effects and are generally well tolerated. There are several myths about taking statins. Talk to your provider to see if statin therapy might be right for you.

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Myths and Facts

Myth:
Statins cause diabetes.
Fact:
People with diabetes benefit the most from statins because they have a higher-than-average risk of having a heart attack or stroke. Statins can increase blood sugar levels, but the overall benefits outweigh this risk. Lifestyle changes of diet and exercise can help keep your blood sugar in a healthy range.
Myth:
Statins cause bad side effects, including muscle aches and weakness.
Fact:
Research has found that most people can tolerate statins and, if they do experience side effects, changing to a different statin, taking a lower dose, or taking every other day may help. It’s important to work with your provider to find the right dose and the right statin. If you previously took a statin that caused muscle pain, talk to your provider about switching to a different statin.
Myth:
Statins cause memory loss.
Fact:
Memory loss and confusion is sometimes reported in people who take statins. Middle-aged and older adults, who are the most common users of statins, sometimes report memory issues. It is hard to tell if it’s the drug or another age-related memory problem. If you do experience confusion or memory loss, your provider can evaluate you and help determine if the symptoms are related to the medication.
Myth:
You can’t eat grapefruit if you take a statin.
Fact:
Grapefruit does change how your body processes statin medications and can increase how much gets into your blood. Not all statins have the same effect with grapefruit, so if you are a grapefruit fan, talk to your provider about taking a statin that is less affected.
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