Make sure to take any medications as your doctor has prescribed to get the most benefit from them. Create a follow up plan so your doctor can determine if the medication is working. B
Below is information on some commonly prescribed medication classes used to treat heart failure.
Diuretics: Also known as “water pills”, diuretics help reduce symptoms like swelling (edema) or difficulty breathing by increasing urination to get rid of excess water and salt (sodium). Some examples of diuretics used for heart failure include furosemide (Lasix®), bumetanide (Bumex®), torsemide, and spironolactone.
Beta-blockers: Beta-blockers lower blood pressure by decreasing heart rate and cardiac output. The most commonly prescribed beta-blockers for heart failure include bisoprolol, carvedilol, and metoprolol succinate extended-release.
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs): ACE inhibitors and ARBs work similarly to widen the blood vessels and decrease the work the heart has to do. They can also help prevent and slow progression of kidney disease. Generic ACE inhibitors names usually end in -pril (e.g., enalapril, captopril, and lisinopril) while generic ARBs usually end in -sartan (e.g., candesartan, losartan, and valsartan).
Angiotensin-receptor neprilysin Inhibitors (ARNIs): Sacubitril/valsartan (Entresto®) is a newer drug combination that helps improve blood flow, decrease strain on the heart, and decrease retention of salt (sodium).
SGLT-2 inhibitors: SGLT-2 inhibitors, such as Jardiance® and Farxiga® ,were initially marketed for treatment of type II diabetes and have been shown to reduce the risk of cardiovascular death and hospitalization in adults with heart failure and reduced ejection fraction.
Statins: The most common cholesterol-lowering medications are HMG CoA reductase inhibitors, also known as “statins.” Statins decrease the body’s production of cholesterol and increase the removal of cholesterol by the liver. They’re most effective at lowering LDL and can also help lower triglycerides and increase HDL. Generic statin names end in -vastatin, including atorvastatin (Lipitor®), pravastatin (Pravachol®), rosuvastatin (Crestor®) and simvastatin (Zocor®). These medications are recommended in patients who have a history of myocardial infarction (MI) or Acute Coronary Syndrome (ACS).
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Healthwise: Heart Failure